Recombinant Human RAC1 Protein, MYC/DDK-tagged

• Cat.No.: RAC1-445H
• Product Overview: Recombinant human RAC1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction. [UniProtKB/Swiss-Prot Function]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 23.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ras-related C3 botulinum toxin substrate 1 [ Homo sapiens ]
• Official Symbol: RAC1
• Synonyms: MIG5; p21-Rac1; Rac-1; TC-25
• Gene ID: 5879
• mRNA Refseq: NM_006908.4
• Protein Refseq: NP_008839.2
• MIM: 602048
• UniProt ID: P63000