Recombinant Human RASGRP3 Protein, GST/His-tagged

• Cat.No.: RASGRP3-405H
• Product Overview: Recombinant Human RASGRP3, transcript variant 2, fused with N-terminal GST and C-terminal His was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers.
• Source: E. coli
• Species: Human
• Tag: GST/His
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 104.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) [ Homo sapiens ]
• Official Symbol: RASGRP3
• Synonyms: RASGRP3; RAS guanyl releasing protein 3 (calcium and DAG-regulated); ras guanyl-releasing protein 3; GRP3; KIAA0846; guanine nucleotide exchange factor for Rap1; calcium and DAG-regulated guanine nucleotide exchange factor III
• Gene ID: 25780
• mRNA Refseq: NM_170672
• Protein Refseq: NP_733772
• MIM: 609531
• UniProt ID: Q8IV61