Recombinant Human RBPJ protein, MYC/DDK-tagged
Cat.No. : | RBPJ-14H |
Product Overview : | Recombinant Human RBPJ, transcript variant 4, fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 54.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | RBPJ recombination signal binding protein for immunoglobulin kappa J region [ Homo sapiens ] |
Official Symbol : | RBPJ |
Synonyms : | RBPJ; recombination signal binding protein for immunoglobulin kappa J region; IGKJRB1, RBPSUH, recombining binding protein suppressor of hairless (Drosophila); recombining binding protein suppressor of hairless; CBF1; IGKJRB; KBF2; RBP J; RBPJK; SUH; suppressor of hairless homolog (Drosophila); CBF-1; RBP-JK; RBP-J kappa; H-2K binding factor-2; suppressor of hairless homolog; renal carcinoma antigen NY-REN-30; immunoglobulin kappa J region recombination signal binding protein 1; csl; RBP-J; RBPSUH; IGKJRB1; MGC61669; |
Gene ID : | 3516 |
mRNA Refseq : | NM_203284 |
Protein Refseq : | NP_976029 |
MIM : | 147183 |
UniProt ID : | Q06330 |
Chromosome Location : | 4p15.2 |
Pathway : | Delta-Notch Signaling Pathway, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Notch Signaling Pathway, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; |
Function : | DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II repressing transcription factor binding; protein binding; recombinase activity; sequence-specific DNA binding transcription factor activity; |
Products Types
◆ Recombinant Protein | ||
Rbpj-5429M | Recombinant Mouse Rbpj Protein, Myc/DDK-tagged | +Inquiry |
RBPJ-2829H | Recombinant Human RBPJ protein(91-170 aa), C-His-tagged | +Inquiry |
RBPJ-3645R | Recombinant Rhesus Macaque RBPJ Protein, His (Fc)-Avi-tagged | +Inquiry |
RBPJ-13H | Recombinant Human RBPJ protein, MYC/DDK-tagged | +Inquiry |
RBPJ-12H | Recombinant Human RBPJ protein, His-tagged | +Inquiry |
◆ Lysates | ||
RBPJ-2453HCL | Recombinant Human RBPJ 293 Cell Lysate | +Inquiry |
RBPJ-2454HCL | Recombinant Human RBPJ 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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