"RFWD2" Related Products

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Recombinant Human RFWD2 protein, MYC/DDK-tagged

Cat.No.: RFWD2-185H
Product Overview: Recombinant Human RFWD2, transcript variant 2, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description: RFWD2 played an important role in many functions.
Source: HEK293
Species: Human
Tag : MYC/DDK
Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass: 77.5 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase [ Homo sapiens ]
Official Symbol: RFWD2
Synonyms: RFWD2; ring finger and WD repeat domain 2, E3 ubiquitin protein ligase; ring finger and WD repeat domain 2; E3 ubiquitin-protein ligase RFWD2; COP1; FLJ10416; RNF200; hCOP1; RING finger protein 200; putative ubiquitin ligase COP1; RING finger and WD repeat domain protein 2; constitutive photomorphogenic protein (COP1); constitutive photomorphogenesis protein 1 homolog; RP11-318C24.3;
Gene ID: 64326
mRNA Refseq: NM_001001740
Protein Refseq: NP_001001740
MIM: 608067
UniProt ID: Q8NHY2
Chromosome Location: 1q25.1-q25.2
Pathway: Autodegradation of the E3 ubiquitin ligase COP1, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; G1/S DNA Damage Checkpoints, organism-specific biosystem; Stabilization of p53, organism-specific biosystem; Ubiquitin mediated proteolysis, organism-specific biosystem;
Function: ligase activity; metal ion binding; protein binding; zinc ion binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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