Recombinant Human RLN2 Protein, His-tagged

• Cat.No.: RLN2-220H
• Product Overview: Recombinant Human RLN2, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects.
• Source: E. coli
• Tag: His
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 20.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RLN2 relaxin 2 [ Homo sapiens ]
• Official Symbol: RLN2
• Synonyms: RLN2; relaxin 2; relaxin 2 (H2); prorelaxin H2; bA12D24.1.1; bA12D24.1.2; H2; relaxin H2; relaxin; ovarian; of pregnancy; RLXH2; relaxin, ovarian, of pregnancy
• Gene ID: 6019
• mRNA Refseq: NM_005059
• Protein Refseq: NP_005050
• MIM: 179740
• UniProt ID: P04090