Recombinant Human RNF168 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RNF168-2245H
• Product Overview: RNF168 MS Standard C13 and N15-labeled recombinant protein (NP_689830) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an E3 ubiquitin ligase protein that contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. The protein is involved in DNA double-strand break (DSB) repair. Mutations in this gene result in Riddle syndrome.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 65 kDa
• AA Sequence: MALPKDAIPSLSECQCGICMEILVE PVTLPCNHTLCKPCFQSTVEKASLC CPFCRRRVSSWTRYHTRRNSLVNVE LWTIIQKHYPRECKLRASGQESEEV ADDYQPVRLLSKPGELRREYEEEIS KVAAERRASEEEENKASEEYIQRLL AEEEEEEKRQAEKRRRAMEEQLKSD EELARKLSIDINNFCEGSISASPLN SRKSDPVTPKSEKKSKNKQRNTGDI QKYLTPKSQFGSASHSEAVQEVRKD SVSKDIDSSDRKSPTGQDTEIEDMP TLSPQISLGVGEQGADSSIESPMPW LCACGAEWYHEGNVKTRPSNHGKEL CVLSHERPKTRVPYSKETAVMPCGR TESGCAPTSGVTQTNGNNTGETENE ESCLLISKEISKRKNQESSFEAVKD PCFSAKRRKVSPESSPDQEETEINF TQKLIDLEHLLFERHKQEEQDRLLA LQLQKEVDKEQMVPNRQKGSPDEYH LRATSSPPDKVLNGQRKNPKDGNFK RQTHTKHPTPERGSRDKNRQVSLKM QLKQSVNRRKMPNSTRDHCKVSKSA HSLQPSISQKSVFQMFQRCTKTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RNF168 ring finger protein 168 [ Homo sapiens (human) ]
• Official Symbol: RNF168
• Synonyms: RNF168; ring finger protein 168, E3 ubiquitin protein ligase; ring finger protein 168; E3 ubiquitin-protein ligase RNF168; FLJ35794; FLJ39749
• Gene ID: 165918
• mRNA Refseq: NM_152617
• Protein Refseq: NP_689830
• MIM: 612688
• UniProt ID: Q8IYW5