Recombinant Human RORA Protein, MYC/DDK-tagged

• Cat.No.: RORA-3931H
• Product Overview: Recombinant protein of human RAR-related orphan receptor A (RORA), transcript variant 1 with a C-Myc/DDK tag was expressed in HEK293 Cells.

Specification

• Description: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene.
• Source: HEK293 Cells
• Species: Human
• Tag: MYC/DDK
• Molecular Mass: 58.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: RORA RAR related orphan receptor A [ Homo sapiens (human) ]
• Official Symbol: RORA
• Synonyms: RORA; RAR related orphan receptor A; ROR1; ROR2; ROR3; RZRA; NR1F1; IDDECA; RZR-ALPHA; nuclear receptor ROR-alpha; ROR-alpha; nuclear receptor RZR-alpha; nuclear receptor subfamily 1 group F member 1; retinoic acid receptor-related orphan receptor alpha
• Gene ID: 6095
• mRNA Refseq: NM_134261
• Protein Refseq: NP_599023
• MIM: 600825
• UniProt ID: P35398