Recombinant Human RPS6KA2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RPS6KA2-3740H
• Product Overview: RPS6KA2 MS Standard C13 and N15-labeled recombinant protein (NP_066958) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternative splice variants, encoding different isoforms, have been characterized.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 83.2 kDa
• AA Sequence: MDLSMKKFAVRRFFSVYLRRKSRSK SSSLSRLEEEGVVKEIDISHHVKEG FEKADPSQFELLKVLGQGSYGKVFL VRKVKGSDAGQLYAMKVLKKATLKV RDRVRSKMERDILAEVNHPFIVKLH YAFQTEGKLYLILDFLRGGDLFTRL SKEVMFTEEDVKFYLAELALALDHL HSLGIIYRDLKPENILLDEEGHIKI TDFGLSKEAIDHDKRAYSFCGTIEY MAPEVVNRRGHTQSADWWSFGVLMF EMLTGSLPFQGKDRKETMALILKAK LGMPQFLSGEAQSLLRALFKRNPCN RLGAGIDGVEEIKRHPFFVTIDWNT LYRKEIKPPFKPAVGRPEDTFHFDP EFTARTPTDSPGVPPSANAHHLFRG FSFVASSLIQEPSQQDLHKVPVHPI VQQLHGNNIHFTDGYEIKEDIGVGS YSVCKRCVHKATDTEYAVKIIDKSK RDPSEEIEILLRYGQHPNIITLKDV YDDGKFVYLVMELMRGGELLDRILR QRYFSEREASDVLCTITKTMDYLHS QGVVHRDLKPSNILYRDESGSPESI RVCDFGFAKQLRAGNGLLMTPCYTA NFVAPEVLKRQGYDAACDIWSLGIL LYTMLAGFTPFANGPDDTPEEILAR IGSGKYALSGGNWDSISDAAKDVVS KMLHVDPHQRLTAMQVLKHPWVVNR EYLSPNQLSRQDVHLVKGAMAATYF ALNRTPQAPRLEPVLSSNLAQRRGM KRLTSTRLSGPTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RPS6KA2 ribosomal protein S6 kinase A2 [ Homo sapiens (human) ]
• Official Symbol: RPS6KA2
• Synonyms: RPS6KA2; ribosomal protein S6 kinase, 90kDa, polypeptide 2; ribosomal protein S6 kinase, 90kD, polypeptide 2; ribosomal protein S6 kinase alpha-2; HU 2; RSK; RSK3; RSK-3; p90RSK2; p90-RSK 2; MAPKAPK-1c; S6K-alpha-2; MAPKAP kinase 1c; ribosomal S6 kinase 3; MAPK-activated protein kinase 1c; ribosomal protein S6 kinase alpha 2; 90 kDa ribosomal protein S6 kinase 2; MAP kinase-activated protein kinase 1c; HU-2; p90-RSK3; pp90RSK3; MAPKAPK1C; S6K-alpha; S6K-alpha2
• Gene ID: 6196
• mRNA Refseq: NM_021135
• Protein Refseq: NP_066958
• MIM: 601685
• UniProt ID: Q15349