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Active Recombinant Human SEMA5B, HIgG1 Fc-tagged

Cat.No. : SEMA5B-002H
Product Overview : The extracellular domain of human SEMA5B (AAH77726.1) (Val78-Thr834) is fused to the N-terminus of the Fc region of human IgG1was expressed in CHO cell
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  • Gene Information
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Description : This gene encodes a member of the semaphorin protein family which regulates axon growth during development of thenervous system. The encoded protein has a characteristic Sema domain near the N-terminus, through whichsemaphorins bind to plexin, and five thrombospondin type 1 repeats in the C-terminal region of the protein. Theprotein product may be cleaved and exist as a secreted molecule (PMID: 19463192). Multiple transcript variantsencoding different isoforms have been found for this gene.
Source : CHO cell
Species : Human
Tag : HIgG1 Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of human pancreatic cancer cells.
Molecular Mass : 110KDa (monomer)
AA Sequence : Val78-Thr834
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B [ Homo sapiens ]
Official Symbol : SEMA5B
Synonyms : SemG; SEMAG
Gene ID : 54437
mRNA Refseq : NM_001256348.1
Protein Refseq : NP_001243277.1
MIM : 609298
UniProt ID : Q9P283
Chromosome Location : 3q21.1
Pathway : Axon guidance, organism-specific biosystem;Axon guidance, conserved biosystem;
Function : receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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