Recombinant Human SGCB Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SGCB-6512H
• Product Overview: SGCB MS Standard C13 and N15-labeled recombinant protein (NP_000223) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 34.8 kDa
• AA Sequence: MAAAAAAAAEQQSSNGPVKKSMREK AVERRSVNKEHNSNFKAGYIPIDED RLHKTGLRGRKGNLAICVIILLFIL AVINLIITLVIWAVIRIGPNGCDSM EFHESGLLRFKQVSDMGVIHPLYKS TVGGRRNENLVITGNNQPIVFQQGT TKLSVENNKTSITSDIGMQFFDPRT QNILFSTDYETHEFHLPSGVKSLNV QKASTERITSNATSDLNIKVDGRAI VRGNEGVFIMGKTIEFHMGGNMELK AENSIILNGSVMVSTTRLPSSSSGD QLGSGDWVRYKLCMCADGTLFKVQV TSQNMGCQISDNPCGNTHTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SGCB sarcoglycan beta [ Homo sapiens (human) ]
• Official Symbol: SGCB
• Synonyms: SGCB; sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); LGMD2E, sarcoglycan, beta (43kD dystrophin associated glycoprotein); beta-sarcoglycan; A3b; SGC; 43DAG; beta-SG; 43 kDa dystrophin-associated glycoprotein; limb girdle muscular dystrophy 2E (non-linked families); beta-sarcoglycan(43kD dystrophin-associated glycoprotein); LGMD2E
• Gene ID: 6443
• mRNA Refseq: NM_000232
• Protein Refseq: NP_000223
• MIM: 600900
• UniProt ID: Q16585