Recombinant Human SIGIRR Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | SIGIRR-2708H |
Product Overview : | SIGIRR MS Standard C13 and N15-labeled recombinant protein (NP_001128525) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 45.7 kDa |
AA Sequence : | MPGVCDRAPDFLSPSEDQVLRPALG SSVALNCTAWVVSGPHCSLPSVQWL KDGLPLGIGGHYSLHEYSWVKANLS EVLVSSVLGVNVTSTEVYGAFTCSI QNISFSSFTLQRAGPTSHVAAVLAS LLVLLALLLAALLYVKCRLNVLLWY QDAYGEVEINDGKLYDAYVSYSDCP EDRKFVNFILKPQLERRRGYKLFLD DRDLLPRAEPSADLLVNLSRCRRLI VVLSDAFLSRAWCSHSFREGLCRLL ELTRRPIFITFEGQRRDPAHPALRL LRQHRHLVTLLLWRPGSVTPSSDFW KEVQLALPRKVRYRPVEGDPQTQLQ DDKDPMLILRGRVPEGRALDSEVDP DPEGDLGVRGPVFGEPSAPPHTSGV SLGESRSSEVDVSDLGSRNYSARTD FYCLVSKDDMSGPTRTRPLEQKLIS EEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | SIGIRR single Ig and TIR domain containing [ Homo sapiens (human) ] |
Official Symbol : | SIGIRR |
Synonyms : | SIGIRR; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; single Ig IL-1-related receptor; single immunoglobulin domain IL1R1 related; TIR8; toll/interleukin-1 receptor 8; single Ig IL-1R-related molecule; single immunoglobulin domain-containing IL1R-related protein; MGC110992; |
Gene ID : | 59307 |
mRNA Refseq : | NM_001135053 |
Protein Refseq : | NP_001128525 |
MIM : | 605478 |
UniProt ID : | Q6IA17 |
Products Types
◆ Recombinant Protein | ||
Sigirr-5875M | Recombinant Mouse Sigirr Protein, Myc/DDK-tagged | +Inquiry |
SIGIRR-4483H | Recombinant Human SIGIRR Protein, His (Fc)-Avi-tagged | +Inquiry |
SIGIRR-2054M | Recombinant Mouse SIGIRR Protein (1-117 aa), His-tagged | +Inquiry |
SIGIRR-5059R | Recombinant Rat SIGIRR Protein, His (Fc)-Avi-tagged | +Inquiry |
Sigirr-10614M | Recombinant Mouse Sigirr Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SIGIRR-1091HCL | Recombinant Human SIGIRR cell lysate | +Inquiry |
SIGIRR-2773MCL | Recombinant Mouse SIGIRR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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