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Recombinant Human SIGLEC8 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : SIGLEC8-1014H
Product Overview : SIGLEC8 MS Standard C13 and N15-labeled recombinant protein (NP_055257) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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  • Gene Information
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Description : Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 ), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM, and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM) that mediates an association with SLAM-associated protein.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 54.1 kDa
AA Sequence : MLLLLLLLPLLWGTKGMEGDRQYGD GYLLQVQELVTVQEGLCVHVPCSFS YPQDGWTDSDPVHGYWFRAGDRPYQ DAPVATNNPDREVQAETQGRFQLLG DIWSNDCSLSIRDARKRDKGSYFFR LERGSMKWSYKSQLNYKTKQLSVFV TALTHRPDILILGTLESGHPRNLTC SVPWACKQGTPPMISWIGASVSSPG PTTARSSVLTLTPKPQDHGTSLTCQ VTLPGTGVTTTSTVRLDVSYPPWNL TMTVFQGDATASTALGNGSSLSVLE GQSLRLVCAVNSNPPARLSWTRGSL TLCPSRSSNPGLLELPRVHVRDEGE FTCRAQNAQGSQHISLSLSLQNEGT GTSRPVSQVTLAAVGGAGATALAFL SFCIIFIIVRSCRKKSARPAAGVGD TGMEDAKAIRGSASQGPLTESWKDG NPLKKPPPAVAPSSGEEGELHYATL SFHKVKPQDPQGQEATDSEYSEIKI HKRETAETQACLRNHNPSSKEVRGT RTRPLEQKLISEEDLAANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : SIGLEC8 sialic acid binding Ig-like lectin 8 [ Homo sapiens (human) ]
Official Symbol : SIGLEC8
Synonyms : SIGLEC8; sialic acid binding Ig-like lectin 8; sialic acid-binding Ig-like lectin 8; MGC59785; SAF2; SIGLEC 8; SIGLEC8L; SAF-2; CDw329; sialoadhesin family member 2; SIGLEC-8;
Gene ID : 27181
mRNA Refseq : NM_014442
Protein Refseq : NP_055257
MIM : 605639
UniProt ID : Q9NYZ4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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