Active Recombinant Human SIRPA protein, mFc-tagged
Cat.No. : | SIRPA-808H |
Product Overview : | Recombinant Human SIRPA protein(Glu 31 - Arg 370), fused with mFc tag, was expressed in HEK293. |
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- Gene Information
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Source : | HEK293 |
Species : | Human |
Tag : | mFc |
Form : | Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5 with trehalose as protectant. |
Bio-activity : | Immobilized Human CD47, His Tag at 2 μg/mL (100 μL/well) can bind Human SIRP alpha, Mouse IgG1 Fc Tag with a linear range of 4-31 ng/mL. Serial dilutions of Anti-Human CD47 Neutralizing Antibody were added into Human SIRP alpha, Mouse IgG1 Fc Tag: Biotinylated Human CD47, Fc,Avitag binding reactions. The half maximal inhibitory concentration (IC50) is 0.2006 μg/mL. |
Molecular Mass : | This protein carries a mouse IgG1 Fc tag at the C-terminusThe protein has a calculated MW of 63.0 kDa. The protein migrates as 70-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein Length : | Glu 31 - Arg 370 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | SIRPA signal-regulatory protein alpha [ Homo sapiens ] |
Official Symbol : | SIRPA |
Synonyms : | SIRPA; signal-regulatory protein alpha; protein tyrosine phosphatase, non receptor type substrate 1 , PTPNS1; tyrosine-protein phosphatase non-receptor type substrate 1; BIT; CD172a; MFR; MYD 1; P84; SHPS 1; SHPS1; SIRP; SIRP ALPHA 1; SIRPalpha; SIRPalpha2; myd-1 antigen; inhibitory receptor SHPS-1; macrophage fusion receptor; CD172 antigen-like family member A; tyrosine phosphatase SHP substrate 1; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; MYD-1; CD172A; PTPNS1; |
Gene ID : | 140885 |
mRNA Refseq : | NM_001040022 |
Protein Refseq : | NP_001035111 |
MIM : | 602461 |
UniProt ID : | P78324 |
Products Types
◆ Recombinant Protein | ||
SIRPA-1158C | Recombinant Cynomolgus SIRPA protein(Met1-Tyr372), His-tagged | +Inquiry |
Sirpa-5882M | Recombinant Mouse Sirpa Protein, Myc/DDK-tagged | +Inquiry |
SIRPA-1388H | Acitve Recombinant Human SIRPA protein(Met1-Arg369), mFc-tagged | +Inquiry |
SIRPA-13H | Active Recombinant Human SIRPA Protein, His-tagged | +Inquiry |
SIRPA-347H | Active Recombinant Human SIRPA Protein, His & Avi-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
SIRPA-2298HCL | Recombinant Human SIRPA cell lysate | +Inquiry |
SIRPA-1650MCL | Recombinant Mouse SIRPA cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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