Description : |
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
52.9 kDa |
AA Sequence : |
MHFSIPETESRSGDSGGSAYVAYNI HVNGVLHCRVRYSQLLGLHEQLRKE YGANVLPAFPPKKLFSLTPAEVEQR REQLEKYMQAVRQDPLLGSSETFNS FLRRAQQETQQVPTEEVSLEVLLSN GQKVLVNVLTSDQTEDVLEAVAAKL DLPDDLIGYFSLFLVREKEDGAFSF VRKLQEFELPYVSVTSLRSQEYKIV LRKSYWDSAYDDDVMENRVGLNLLY AQTVSDIERGWILVTKEQHRQLKSL QEKVSKKEFLRLAQTLRHYGYLRFD ACVADFPEKDCPVVVSAGNSELSLQ LRLPGQQLREGSFRVTRMRCWRVTS SVPLPSGSTSSPGRGRGEVRLELAF EYLMSKDRLQWVTITSPQAIMMSIC LQSMVDELMVKKSGGSIRKMLRRRV GGTLRRSDSQQAVKSPPLLESPDAT RESMVKLSSKLSAVSLRGIGSPSTD ASASDVHGNFAFEGIGDEDLTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |