| Description : |
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
79.4 kDa |
| AA Sequence : |
MSLSMRDPVIPGTSMAYHPFLPHRA PDFAMSAVLGHQPPFFPALTLPPNG AAALSLPGALAKPIMDQLVGAAETG IPFSSLGPQAHLRPLKTMEPEEEVE DDPKVHLEAKELWDQFHKRGTEMVI TKSGRRMFPPFKVRCSGLDKKAKYI LLMDIIAADDCRYKFHNSRWMVAGK ADPEMPKRMYIHPDSPATGEQWMSK VVTFHKLKLTNNISDKHGFTLAFPS DHATWQGNYSFGTQTILNSMHKYQP RFHIVRANDILKLPYSTFRTYLFPE TEFIAVTAYQNDKITQLKIDNNPFA KGFRDTGNGRREKRKQLTLQSMRVF DERHKKENGTSDESSSEQAAFNCFA QASSPAASTVGTSNLKDLCPSEGES DAEAESKEEHGPEACDAAKISTTTS EEPCRDKGSPAVKAHLFAAERPRDS GRLDKASPDSRHSPATISSSTRGLG AEERRSPVREGTAPAKVEEARALPG KEAFAPLTVQTDAAAAHLAQGPLPG LGFAPGLAGQQFFNGHPLFLHPSQF AMGGAFSSMAAAGMGPLLATVSGAS TGVSGLDSTAMASAAAAQGLSGASA ATLPFHLQQHVLASQGLAMSPFGSL FPYPYTYMAAAAAASSAAASSSVHR HPFLNLNTMRPRLRYSPYSIPVPVP DGSSLLTTALPSMAAAAGPLDGKVA ALAASPASVAVDSGSELNSRSSTLS SSSMSLSPKLCAEKEAATSELQSIQ RLVSGLEAKPDRSRSASPTRTRPLE QKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
