Recombinant Human TDP2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TDP2-6706H
• Product Overview: TTRAP MS Standard C13 and N15-labeled recombinant protein (NP_057698) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 40.9 kDa
• AA Sequence: MELGSCLEGGREAAEEEGEPEVKKR RLLCVEFASVASCDAAVAQCFLAEN DWEMERALNSYFEPPVEESALERRP ETISEPKTYVDLTNEETTDSTTSKI SPSEDTQQENGSMFSLITWNIDGLD LNNLSERARGVCSYLALYSPDVIFL QEVIPPYYSYLKKRSSNYEIITGHE EGYFTAIMLKKSRVKLKSQEIIPFP STKMMRNLLCVHVNVSGNELCLMTS HLESTRGHAAERMNQLKMVLKKMQE APESATVIFAGDTNLRDREVTRCGG LPNNIVDVWEFLGKPKHCQYTWDTQ MNSNLGITAACKLRFDRIFFRAAAE EGHIIPRSLDLLGLEKLDCGRFPSD HWGLLCNLDIILTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TDP2 tyrosyl-DNA phosphodiesterase 2 [ Homo sapiens (human) ]
• Official Symbol: TDP2
• Synonyms: TDP2; tyrosyl-DNA phosphodiesterase 2; TRAF and TNF receptor associated protein, TTRAP; ETS1-associated protein 2; ETS1-associated protein II; tyr-DNA phosphodiesterase 2; 5-Tyr-DNA phosphodiesterase; 5-tyrosyl-DNA phosphodiesterase; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; EAP2; AD022; EAPII; TTRAP; dJ30M3.3; RP1-30M3.3; MGC9099; MGC111021
• Gene ID: 51567
• mRNA Refseq: NM_016614
• Protein Refseq: NP_057698
• MIM: 605764
• UniProt ID: O95551