Recombinant Human TGFBR2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | TGFBR2-4439H |
Product Overview : | TGFBR2 MS Standard C13 and N15-labeled recombinant protein (NP_003233) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with TGF-beta receptor type-1, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of genes related to cell proliferation, cell cycle arrest, wound healing, immunosuppression, and tumorigenesis. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 64.57 kDa |
AA Sequence : | MGRGLLRGLWPLHIVLWTRIASTIP PHVQKSVNNDMIVTDNNGAVKFPQL CKFCDVRFSTCDNQKSCMSNCSITS ICEKPQEVCVAVWRKNDENITLETV CHDPKLPYHDFILEDAASPKCIMKE KKKPGETFFMCSCSSDECNDNIIFS EEYNTSNPDLLLVIFQVTGISLLPP LGVAISVIIIFYCYRVNRQQKLSST WETGKTRKLMEFSEHCAIILEDDRS DISSTCANNINHNTELLPIELDTLV GKGRFAEVYKAKLKQNTSEQFETVA VKIFPYEEYASWKTEKDIFSDINLK HENILQFLTAEERKTELGKQYWLIT AFHAKGNLQEYLTRHVISWEDLRKL GSSLARGIAHLHSDHTPCGRPKMPI VHRDLKSSNILVKNDLTCCLCDFGL SLRLDPTLSVDDLANSGQVGTARYM APEVLESRMNLENVESFKQTDVYSM ALVLWEMTSRCNAVGEVKDYEPPFG SKVREHPCVESMKDNVLRDRGRPEI PSFWLNHQGIQMVCETLTECWDHDP EARLTAQCVAERFSELEHLDRLSGR SCSEEKIPEDGSLNTTKSGPTRTRR LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | TGFBR2 transforming growth factor beta receptor 2 [ Homo sapiens (human) ] |
Official Symbol : | TGFBR2 |
Synonyms : | TGFBR2; transforming growth factor, beta receptor II (70/80kDa); MFS2, transforming growth factor, beta receptor II (70 80kD); TGF-beta receptor type-2; tbetaR-II; TGF-beta receptor type II; TGF-beta type II receptor; TGF-beta receptor type IIB; transforming growth factor-beta receptor type II; transforming growth factor beta receptor type IIC; transforming growth factor, beta receptor II (70/80kDa) isoform 1; transforming growth factor, beta receptor II (70/80kDa) isoform 2; AAT3; FAA3; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII; |
Gene ID : | 7048 |
mRNA Refseq : | NM_003242 |
Protein Refseq : | NP_003233 |
MIM : | 190182 |
UniProt ID : | P37173 |
Products Types
◆ Recombinant Protein | ||
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TGFBR2-703H | Recombinant Human TGFBR2 Protein, MYC/DDK-tagged | +Inquiry |
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Tgfbr2-6393M | Recombinant Mouse Tgfbr2 Protein, Myc/DDK-tagged | +Inquiry |
TGFBR2-4503R | Recombinant Rhesus Macaque TGFBR2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TGFBR2-1291CCL | Recombinant Cynomolgus TGFBR2 cell lysate | +Inquiry |
TGFBR2-2842HCL | Recombinant Human TGFBR2 cell lysate | +Inquiry |
TGFBR2-1374RCL | Recombinant Rat TGFBR2 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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