Active Recombinant Human TGFBR3

• Cat.No.: TGFBR3-193H
• Product Overview: Recombinant Human TGFBR3 (Accession # AAA67061.1) Gly21-Asp781 was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Predicted N Terminal: Gly21
• Form: Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
• Bio-activity: Measured by its ability to inhibit TGF-beta 2 activity on HT-2 mouse T cells. Tsang, M. et al. (1995) Cytokine 7:389.The ED50 for this effect is typically 20 - 50 ng/mL in the presence of 0.4 ng/mL of rhTGF-beta 2.
• Molecular Mass: Recombinant Human TGFBR3 has a calculated MW of 84 kDa. In SDS-PAGE migrates as 100 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 200 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: TGFBR3 transforming growth factor, beta receptor III [ Homo sapiens ]
• Official Symbol: TGFBR3
• Synonyms: TGFBR3; transforming growth factor, beta receptor III; transforming growth factor, beta receptor III (betaglycan, 300kDa); transforming growth factor beta receptor type 3; betaglycan; betaglycan proteoglycan; BGCAN; TGFR-3; TGF-beta receptor type 3; TGF-beta receptor type III
• Gene ID: 7049
• mRNA Refseq: NM_001195683
• Protein Refseq: NP_001182612
• MIM: 600742
• UniProt ID: Q03167
• Chromosome Location: 1p33-p32