"TIE1" Related Products

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Recombinant Human TIE1 Protein, DDK/His-tagged

Cat.No.: TIE1-600H
Product Overview: Recombinant Human TIE1(Ala22 – Gln759) fused with DDK/His tag at C-terminal was expressed in HEK293 cells.
Description: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Source: HEK293 cells
Species: Human
Tag : DDK/His
Form: 1 x PBS, pH7.4, 10% glycerol.
Molecular Mass: 82.6 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Gene Name: TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 [ Homo sapiens ]
Official Symbol: TIE1
Synonyms: TIE1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; TIE, tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1; tyrosine-protein kinase receptor Tie-1; JTK14; tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1; TIE;
Gene ID: 7075
mRNA Refseq: NM_001253357
Protein Refseq: NP_001240286
MIM: 600222
UniProt ID: P35590

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