Active Recombinant Human TMPRSS2 Protein, His-tagged
Cat.No. : | TMPRSS2-02H |
Product Overview : | Rcombinant Human TMPRSS2 [106-492 aa(R255Q)] Protein with a N-terminal 10xHis-tag was expressed in mammalian cell. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein signals through the RET receptor and GFR alpha 3 coreceptor, and supports the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Mice lacking a functional copy of this gene exhibit ptosis and impaired development of the sympathetic nervous system. |
Source : | Mammalian cell |
Species : | Human |
Tag : | His |
Form : | Lyophilized powder |
Bio-activity : | Recombinant Human TMPRSS2 His tag protein enzyme activity is measured by its ability to cleave fluorogenic peptide substrate(Boc-Gln-Ala-Arg-AMC), The Km is 19.16μM. |
Molecular Mass : | 47.8 kDa |
Protein length : | 106-492 |
AA Sequence : | WKFMGSKCSNSGIECDSSGTCINPS NWCDGVSHCPGGEDENRCVRLYGPN FILQVYSSQRKSWHPVCQDDWNENY GRAACRDMGYKNNFYSSQGIVDDSG STSFMKLNTSAGNVDIYKKLYHSDA CSSKAVVSLRCIACGVNLNSSRQSQ IVGGESALPGAWPWQVSLHVQNVHV CGGSIITPEWIVTAAHCVEKPLNNP WHWTAFAGILRQSFMFYGAGYQVEK VISHPNYDSKTKNNDIALMKLQKPL TFNDLVKPVCLPNPGMMLQPEQLCW ISGWGATEEKGKTSEVLNAAKVLLI ETQRCNSRYVYDNLITPAMICAGFL QGNVDSCQGDSGGPLVTSKNNIWWL IGDTSWGSGCAKAYRPGVYGNVMVF TDWIYRQMRADG |
Endotoxin : | <1.0 EU/μg of the protein by the LAL method. |
Purity : | ≥85% by SDS-PAGE quantitative densitometry by Coomassie Blue Staining |
Stability : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20/-80 centigrade. The shelf life of lyophilized form is 12 months at -20/-80 centigrade. |
Storage : | Short term: 2 to 8 centigrade, one week after reconstitution Long term: -20 to -80 centigrade, twelve months from the date of receipt |
Storage Buffer : | Lyophilized from a 0.2 μm sterile filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0. The volume before lyophilization is 20μL/vial. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20/-80 centigrade. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Gene Name : | TMPRSS2 transmembrane serine protease 2 [ Homo sapiens (human) ] |
Official Symbol : | TMPRSS2 |
Synonyms : | TMPRSS2; transmembrane serine protease 2; PRSS10; transmembrane protease serine 2; epitheliasin; serine protease 10; transmembrane protease, serine 2; EC 3.4.21.- |
Gene ID : | 7113 |
mRNA Refseq : | NM_005656 |
Protein Refseq : | NP_005647 |
MIM : | 602060 |
UniProt ID : | O15393 |
Products Types
◆ Recombinant Protein | ||
TMPRSS2-13H | Recombinant Active Human TMPRSS2 Protein (107-492), N-FLAG and C-Myc/His-tagged | +Inquiry |
TMPRSS2-05943H | Recombinant Human TMPRSS2 Protein(106-492aa), MBP&His-Avi-tagged, Biotinylated | +Inquiry |
Tmprss2-429R | Recombinant Rat Tmprss2 Protein, His-tagged | +Inquiry |
Tmprss2-428M | Recombinant Mouse Tmprss2 Protein, His-tagged | +Inquiry |
TMPRSS2-05944H | Recombinant Human TMPRSS2 Protein(256-492aa), GST-tagged | +Inquiry |
◆ Lysates | ||
TMPRSS2-910HCL | Recombinant Human TMPRSS2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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