Recombinant Human TNFRSF13B protein, Fc-tagged
Cat.No. : | TNFRSF13B-359H |
Product Overview : | Recombinant Human TNFRSF13B protein (Ser2-Thr166), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
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- Gene Information
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Description : | Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells. |
Source : | HEK293 |
Species : | Human |
Tag : | human IgG1 Fc |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 44.6 kDa. The protein migrates as 36 kDa, 37 kDa and 46 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 165 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >90% as determined by reduced SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | TNFRSF13B |
Official Symbol : | TNFRSF13B |
Synonyms : | TNFRSF13B; tumor necrosis factor receptor superfamily, member 13B; tumor necrosis factor receptor superfamily member 13B; CD267; TACI; tumor necrosis factor receptor 13B; transmembrane activator and CAML interactor; CVID; CVID2; TNFRSF14B; FLJ39942; MGC39952; MGC133214 |
Gene ID : | 23495 |
mRNA Refseq : | NM_012452 |
Protein Refseq : | NP_036584 |
MIM : | 604907 |
UniProt ID : | O14836 |
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◆ Lysates | ||
TNFRSF13B-1916HCL | Recombinant Human TNFRSF13B cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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