| Description : |
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
69.4 kDa |
| AA Sequence : |
MAQSTATSPDGGTTFEHLWSSLEPD STYFDLPQSSRGNNEVVGGTDSSMD VFHLEGMTTSVMAQFNLLSSTMDQM SSRAASASPYTPEHAASVPTHSPYA QPSSTFDTMSPAPVIPSNTDYPGPH HFEVTFQQSSTAKSATWTYSPLLKK LYCQIAKTCPIQIKVSTPPPPGTAI RAMPVYKKAEHVTDVVKRCPNHELG RDFNEGQSAPASHLIRVEGNNLSQY VDDPVTGRQSVVVPYEPPQVGTEFT TILYNFMCNSSCVGGMNRRPILIII TLEMRDGQVLGRRSFEGRICACPGR DRKADEDHYREQQALNESSAKNGAA SKRAFKQSPPAVPALGAGVKKRRHG DEDTYYLQVRGRENFEILMKLKESL ELMELVPQPLVDSYRQQQQLLQRPS HLQPPSYGPVLSPMNKVHGGMNKLP SVNQLVGQPPPHSSAATPNLGPVGP GMLNNHGHAVPANGEMSSSHSAQSM VSGSHCTPPPPYHADPSLVSFLTGL GCPNCIEYFTSQGLQSIYHLQNLTI EDLGALKIPEQYRMTIWRGLQDLKQ GHDYSTAQQLLRSSNAATISIGGSG ELQRQRVMEAVHFRVRHTITIPNRG GPGGGPDEWADFGFDLPDCKARKQP IKEEFTEAEIHTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
