|Product Overview:||Recombinant human TREM-2 (His19-Ser174) protein with a C-terminal 6-His tag was expressed in mouse myeloma cell line.|
|Description:||May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.|
|Predicted N Terminal:||His19|
|Bio-activity:||Measured by its ability to bind fluorescein-conjugated E. coli Bioparticles. The ED50 for this effect is 0.15-0.9 μg/mL using a His Tag Antibody coated plate.|
|Molecular Mass:||Predicted Molecular Mass: 18 kDa
SDS-PAGE: 25-39 kDa, reducing conditions
|N-terminal Sequence Analysis:||His|
|Endotoxin:||<0.10 EU per 1 μg of the protein by the LAL method.|
|Purity:||>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.|
|Storage:||Avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
|Storage Buffer:||Lyophilized from a 0.2 μm filtered solution in HEPES and NaCl.|
|Reconstitution:||Reconstitute at 500 μg/mL in water.|
|Official Symbol:||TREM2 triggering receptor expressed on myeloid cells 2 [ Homo sapiens (human) ]|
|Synonyms:||TREM2; TREM-2; Trem2a; Trem2b; Trem2c; TREM-2triggering receptor expressed on myeloid cells 2a; Triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2; triggering receptor expressed on myeloid cells 2; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a|