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Recombinant Human TSHB protein, MYC/DDK-tagged

Cat.No. : TSHB-185H
Product Overview : Recombinant Human TSHB fused with MYC/DDK tag at C-terminal was expressed in HEK293.
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Description : The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 13.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : TSHB thyroid stimulating hormone, beta [ Homo sapiens ]
Official Symbol : TSHB
Synonyms : TSHB; thyroid stimulating hormone, beta; thyrotropin subunit beta; thyrotropin beta chain; thyrotropin beta subunit; thyroid-stimulating hormone subunit beta; TSH-B; TSH-BETA;
Gene ID : 7252
mRNA Refseq : NM_000549
Protein Refseq : NP_000540
MIM : 188540
UniProt ID : P01222

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there specific populations or conditions where TSHB protein assessment is particularly important? 03/09/2023

TSHB protein assessment is crucial in pregnant women, as thyroid function is vital for fetal development, and abnormalities can impact both the mother and the baby.

Can TSHB protein assessment be part of routine health check-ups? 04/19/2021

Yes, measuring TSHB protein levels is often included in routine thyroid function tests during health check-ups.

Can TSHB protein levels be indicative of autoimmune thyroid diseases? 03/08/2019

Yes, elevated TSHB levels may be associated with autoimmune thyroid diseases like Hashimoto's thyroiditis or Graves' disease.

How does the TSHB protein contribute to the management of thyroid cancer? 03/19/2017

TSHB protein levels are monitored to help manage thyroid cancer patients, especially after thyroidectomy, to ensure that thyroid-stimulating hormone levels are within a target range.

Are there advancements in technology or methods for measuring TSHB levels in clinical settings? 06/06/2016

Yes, advancements include highly sensitive immunoassays and molecular techniques that enhance the accuracy and efficiency of TSHB protein measurement.

Customer Reviews (3)

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Reviews
08/25/2021

    Researchers can feel confident in the reliability and efficacy of the TSHB protein and rely on the manufacturer's expertise to navigate any challenges that may arise during their trials.

    07/07/2019

      The manufacturer's commitment to excellence is evident through their provision of excellent technical support, which can prove vital in troubleshooting any experimental challenges or addressing specific research questions related to the protein.

      10/08/2017

        the TSHB protein's quality and suitability for experimental needs, combined with the manufacturer's excellent technical support, create a valuable partnership that enhances research outcomes.

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