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Recombinant Human UBE2N Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : UBE2N-1221H
Product Overview : UBE2N MS Standard C13 and N15-labeled recombinant protein (NP_003339) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 17.1 kDa
AA Sequence : MAGLPRRIIKETQRLLAEPVPGIKA EPDESNARYFHVVIAGPQDSPFEGG TFKLELFLPEEYPMAAPKVRFMTKI YHPNVDKLGRICLDILKDKWSPALQ IRTVLLSIQALLSAPNPDDPLANDV AEQWKTNEAQAIETARAWTRLYAMN NITRTRPLEQKLISEEDLAANDILD YKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : UBE2N ubiquitin-conjugating enzyme E2N [ Homo sapiens (human) ]
Official Symbol : UBE2N
Synonyms : UBE2N; ubiquitin-conjugating enzyme E2N; ubiquitin conjugating enzyme E2N (homologous to yeast UBC13), ubiquitin conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-conjugating enzyme E2 N; MGC8489; UBC13; UbcH ben; yeast UBC13 homolog; ubiquitin-protein ligase N; ubiquitin carrier protein N; bendless-like ubiquitin conjugating enzyme; bendless-like ubiquitin-conjugating enzyme; ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13); UbcH-ben; MGC131857;
Gene ID : 7334
mRNA Refseq : NM_003348
Protein Refseq : NP_003339
MIM : 603679
UniProt ID : P61088

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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