Recombinant Human UCHL1 Protein, Myc/DDK-tagged
Cat.No. : | UCHL1-20H |
Product Overview : | Recombinant human UCHL1 protein with a C-terminal Myc/DDK-tag was expressed in HEK293T. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease. |
Source : | HEK293T |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 24.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles |
Storage : | Store it at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris. HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name : | UCHL1 ubiquitin C-terminal hydrolase L1 [ Homo sapiens (human) ] |
Official Symbol : | UCHL1 |
Synonyms : | UCHL1; ubiquitin C-terminal hydrolase L1; NDGOA; PARK5; PGP95; SPG79; PGP9.5; Uch-L1; HEL-117; PGP 9.5; HEL-S-53; ubiquitin carboxyl-terminal hydrolase isozyme L1; epididymis luminal protein 117; epididymis secretory protein Li 53; neuron cytoplasmic protein 9.5; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); ubiquitin thioesterase L1; ubiquitin thiolesterase |
Gene ID : | 7345 |
mRNA Refseq : | NM_004181 |
Protein Refseq : | NP_004172 |
MIM : | 191342 |
UniProt ID : | P09936 |
Products Types
◆ Recombinant Protein | ||
UCHL1-2619H | Recombinant Human UCHL1 protein(61-150 aa), C-His-tagged | +Inquiry |
UCHL1-2618H | Recombinant Human UCHL1 protein(71-150 aa), C-His-tagged | +Inquiry |
UCHL1-1339S | Recombinant Human UCHL1 Protein (Q2-A223), His tagged | +Inquiry |
Uchl1-6819M | Recombinant Mouse Uchl1 Protein, Myc/DDK-tagged | +Inquiry |
UCHL1-9868M | Recombinant Mouse UCHL1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
UCHL1-535HCL | Recombinant Human UCHL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionEarly research suggests that changes in UCHL1 levels may be detected in the early stages of some neurodegenerative diseases, but more studies are needed for validation.
While UCHL1 is primarily associated with neurological functions, it also has roles in non-neuronal tissues, including certain types of cancer cells.
Challenges include the need for standardized assays, variations in UCHL1 levels among individuals, and the influence of other factors on its expression.
Yes, elevated or decreased levels of UCHL1 in cerebrospinal fluid or blood may serve as potential biomarkers for certain neurological disorders.
UCHL1 dysfunction has been implicated in conditions such as certain cancers and ischemic stroke.
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Write a reviewWhether it is regarding experimental design, optimization of protocols, or troubleshooting issues, their expertise and prompt customer service help researchers overcome challenges efficiently.
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