|Product Overview :
||Recombinant human UNC5B protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
||This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011].
||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
|Molecular Mass :
||> 80% as determined by SDS-PAGE and Coomassie blue staining
||>50 ug/mL as determined by microplate BCA method