| Description : |
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
102.9 kDa |
| AA Sequence : |
MRKGLRATAARCGLGLGYLLQMLVL PALALLSASGTGSAAQDDDFFHELP ETFPSDPPEPLPHFLIEPEEAYIVK NKPVNLYCKASPATQIYFKCNSEWV HQKDHIVDERVDETSGLIVREVSIE ISRQQVEELFGPEDYWCQCVAWSSA GTTKSRKAYVRIAYLRKTFEQEPLG KEVSLEQEVLLQCRPPEGIPVAEVE WLKNEDIIDPVEDRNFYITIDHNLI IKQARLSDTANYTCVAKNIVAKRKS TTATVIVYVNGGWSTWTEWSVCNSR CGRGYQKRTRTCTNPAPLNGGAFCE GQSVQKIACTTLCPVDGRWTPWSKW STCGTECTHWRRRECTAPAPKNGGK DCDGLVLQSKNCTDGLCMQTAPDSD DVALYVGIVIAVIVCLAISVVVALF VYRKNHRDFESDIIDSSALNGGFQP VNIKAARQDLLAVPPDLTSAAAMYR GPVYALHDVSDKIPMTNSPILDPLP NLKIKVYNTSGAVTPQDDLSEFTSK LSPQMTQSLLENEALSLKNQSLARQ TDPSCTAFGSFNSLGGHLIVPNSGV SLLIPAGAIPQGRVYEMYVTVHRKE TMRPPMDDSQTLLTPVVSCGPPGAL LTRPVVLTMHHCADPNTEDWKILLK NQAAQGQWEDVVVVGEENFTTPCYI KLDAEACHILTENLSTYALVGHSTT KAAAKRLKLAIFGPLCCSSLEYSIR VYCLDDTQDALKEILHLERQTGGQL LEEPKALHFKGSTHNLRLSIHDIAH SLWKSKLLAKYQEIPFYHVWSGSQR NLHCTFTLERFSLNTVELVCKLCVR QVEGEGQIFQLNCTVSEEPTGIDLP LLDPANTITTVTGPSAFSIPLPIRQ KLCSSLDAPQTRGHDWRMLAHKLNL DRYLNYFATKSSPTGVILDLWEAQN FPDGNLSMLAAVLEEMGRHETVVSL AAEGQYTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
