Recombinant Human UPF1 Protein, MYC/DDK-tagged
Cat.No. : | UPF1-635H |
Product Overview : | Recombinant human UPF1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 122.9 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | UPF1, RNA helicase and ATPase[ Homo sapiens ] |
Official Symbol : | UPF1 |
Synonyms : | HUPF1; NORF1; pNORF1; RENT1; smg-2 |
Gene ID : | 5976 |
mRNA Refseq : | NM_002911.3 |
Protein Refseq : | NP_002902.2 |
MIM : | 601430 |
UniProt ID : | Q92900 |
Products Types
◆ Recombinant Protein | ||
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UPF1-9926M | Recombinant Mouse UPF1 Protein, His (Fc)-Avi-tagged | +Inquiry |
UPF1-12641Z | Recombinant Zebrafish UPF1 | +Inquiry |
UPF1-3089H | Recombinant Human UPF1 protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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