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Active Recombinant Human USP8

Cat.No. : USP8-127H
Product Overview : Recombinant Human USP8 was expressed in E.coli
  • Specification
  • Gene Information
  • Related Products
Description : Ubiquitin carboxyl-terminal hydrolase 8 is an enzyme that in humans is encoded by the USP8 gene.
Source : E. coli
Species : Human
Form : 50 mM HEPES pH 7.5, 150 mM sodium chloride, 2 mM dithiothreitol, 10% glycerol
Bio-activity : Deubiquitylase Enzyme Assay: The activity of USP8 was validated by determining the increase in fluorescence measured as a result of the enzyme catalysed cleavage of the fluorogenic substrate Ubiquitin-Rhodamine110-Glycine generating Ubiquitin and Rhodamine110-Glycine. Incubation of the substrate in the presence or absence of USP8 was compared confirming the deubiquitylating activity of USP8.
Molecular Mass : ~128kDa
Purity : >66% by InstantBlue™ SDS-PAGE
Storage : 12 months at -70℃; aliquot as required.
Concentration : 0.5 mg/ml
Gene Name : USP8 ubiquitin specific peptidase 8 [ Homo sapiens ]
Official Symbol : USP8
Synonyms : USP8; ubiquitin specific peptidase 8; ubiquitin specific protease 8; ubiquitin carboxyl-terminal hydrolase 8; HumORF8; KIAA0055; UBPY; hUBPy; ubiquitin isopeptidase Y; ubiquitin thioesterase 8; deubiquitinating enzyme 8; ubiquitin thiolesterase 8; ubiquitin-specific-processing protease 8; FLJ34456; MGC129718;
Gene ID : 9101
mRNA Refseq : NM_001128610
Protein Refseq : NP_001122082
MIM : 603158
UniProt ID : P40818
Chromosome Location : 15q21.1
Pathway : Downregulation of ERRB2:ERBB3 signaling, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; ErbB2/ErbB3 signaling events, organism-specific biosystem; Internalization of ErbB1, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by ERBB2, organism-specific biosystem;
Function : SH3 domain binding; cysteine-type endopeptidase activity; peptidase activity; protein binding; ubiquitin thiolesterase activity; ubiquitin-specific protease activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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