| Description : |
This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
53.5 kDa |
| AA Sequence : |
MSTRSVSSSSYRRMFGGPGTASRPS SSRSYVTTSTRTYSLGSALRPSTSR SLYASSPGGVYATRSSAVRLRSSVP GVRLLQDSVDFSLADAINTEFKNTR TNEKVELQELNDRFANYIDKVRFLE QQNKILLAELEQLKGQGKSRLGDLY EEEMRELRRQVDQLTNDKARVEVER DNLAEDIMRLREKLQEEMLQREEAE NTLQSFRQDVDNASLARLDLERKVE SLQEEIAFLKKLHEEEIQELQAQIQ EQHVQIDVDVSKPDLTAALRDVRQQ YESVAAKNLQEAEEWYKSKFADLSE AANRNNDALRQAKQESTEYRRQVQS LTCEVDALKGTNESLERQMREMEEN FAVEAANYQDTIGRLQDEIQNMKEE MARHLREYQDLLNVKMALDIEIATY RKLLEGEESRISLPLPNFSSLNLRE TNLDSLPLVDTHSKRTLLIKTVETR DGQVINETSQHHDDLETRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
