| Description : |
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
107.6 kDa |
| AA Sequence : |
MAAYLQWRRFVFFDKELVKEPLSND GAAPGATPASGSAASKFLCLPPGIT VCDSGRGSLVFGDMEGQIWFLPRSL QLTGFQAYKLRVTHLYQLKQHNILA SVGEDEEGINPLVKIWNLEKRDGGN PLCTRIFPAIPGTEPTVVSCLTVHE NLNFMAIGFTDGSVTLNKGDITRDR HSKTQILHKGNYPVTGLAFRQAGKT THLFVVTTENVQSYIVSGKDYPRVE LDTHGCGLRCSALSDPSQDLQFIVA GDECVYLYQPDERGPCFAFEGHKLI AHWFRGYLIIVSRDRKVSPKSEFTS RDSQSSDKQILNIYDLCNKFIAYST VFEDVVDVLAEWGSLYVLTRDGRVH ALQEKDTQTKLEMLFKKNLFEMAIN LAKSQHLDSDGLAQIFMQYGDHLYS KGNHDGAVQQYIRTIGKLEPSYVIR KFLDAQRIHNLTAYLQTLHRQSLAN ADHTTLLLNCYTKLKDSSKLEEFIK KKSESEVHFDVETAIKVLRQAGYYS HALYLAENHAHHEWYLKIQLEDIKN YQEALRYIGKLPFEQAESNMKRYGK ILMHHIPEQTTQLLKGLCTDYRPSL EGRSDREAPGCRANSEEFIPIFANN PRELKAFLEHMSEVQPDSPQGIYDT LLELRLQNWAHEKDPQVKEKLHAEA ISLLKSGRFCDVFDKALVLCQMHDF QDGVLYLYEQGKLFQQIMHYHMQHE QYRQVISVCERHGEQDPSLWEQALS YFARKEEDCKEYVAAVLKHIENKNL MPPLLVVQTLAHNSTATLSVIRDYL VQKLQKQSQQIAQDELRVRRYREET TRIRQEIQELKASPKIFQKTKCSIC NSALELPSVHFLCGHSFHQHCFESY SESDADCPTCLPENRKVMDMIRAQE QKRDLHDQFQHQLRCSNDSFSVIAD YFGRGVFNKLTLLTDPPTARLTSSL EAGLQRDLLMHSRRGTTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
