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Recombinant Human WDR59 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : WDR59-2238H
Product Overview : WDR59 MS Standard C13 and N15-labeled recombinant protein (NP_085058) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 109.6 kDa
AA Sequence : MAARWSSENVVVEFRDSQATAMSVD CLGQHAVLSGRRFLYIVNLDAPFEG HRKISRQSKWDIGAVQWNPHDSFAH YFAASSNQRVDLYKWKDGSGEVGTT LQGHTRVISDLDWAVFEPDLLVTSS VDTYIYIWDIKDTRKPTVALSAVAG ASQVKWNKKNANCLATSHDGDVRIW DKRKPSTAVEYLAAHLSKIHGLDWH PDSEHILATSSQDNSVKFWDYRQPR KYLNILPCQVPVWKARYTPFSNGLV TVMVPQLRRENSLLLWNVFDLNTPV HTFVGHDDVVLEFQWRKQKEGSKDY QLVTWSRDQTLRMWRVDSQMQRLCA NDILDGVDEFIESISLLPEPEKTLH TEDTDHQHTASHGEEEALKEDPPRN LLEERKSDQLGLPQTLQQEFSLINV QIRNVNVEMDAADRSCTVSVHCSNH RVKMLVKFPAQYPNNAAPSFQFINP TTITSTMKAKLLKILKDTALQKVKR GQSCLEPCLRQLVSCLESFVNQEDS ASSNPFALPNSVTPPLPTFARVTTA YGSYQDANIPFPRTSGARFCGAGYL VYFTRPMTMHRAVSPTEPTPRSLSA LSAYHTGLIAPMKIRTEAPGNLRLY SGSPTRSEKEQVSISSFYYKERKSR RWKSKREGSDSGNRQIKAAGKVIIQ DIACLLPVHKSLGELYILNVNDIQE TCQKNAASALLVGRKDLVQVWSLAT VATDLCLGPKSDPDLETPWARHPFG RQLLESLLAHYCRLRDVQTLAMLCS VFEAQSRPQGLPNPFGPFPNRSSNL VVSHSRYPSFTSSGSCSSMSDPGLN TGGWNIAGREAEHLSSPWGESSPEE LRFGSLTYSDPRERERDQHDKNKRL LDPANTQQFDDFKKCYGEILYRWGL REKRAEVLKFVSCPPDPHKGIEFGV YCSHCRSEVRGTQCAICKGFTFQCA ICHVAVRGSSNFCLTCGHGGHTSHM MEWFRTQEVCPTGCGCHCLLESTFT RTRPLEQKLISEEDLAANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : WDR59 WD repeat domain 59 [ Homo sapiens (human) ]
Official Symbol : WDR59
Synonyms : WDR59; WD repeat domain 59; WD repeat-containing protein 59; FLJ12270; FP977; MGC11230;
Gene ID : 79726
mRNA Refseq : NM_030581
Protein Refseq : NP_085058
MIM : 617418
UniProt ID : Q6PJI9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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