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Active Recombinant Human WNT7A Protein

Cat.No. : WNT7A-121H
Product Overview : The mature recombinant human Wnt-7a protein containing 318aa (L32-K349) without tag was expressed in E. coli.
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  • Gene Information
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Description : This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes.
Source : E. coli
Species : Human
Bio-activity : Measured by its ability to inhibit Wnt-3a-induced alkaline phosphatase production by MC3T3-E1 mouse preosteoblast cells. The ED50 for this effect is 1-3 μg/mL in the presence of 5 ng/mL recombinant mouse Wnt-3a.
Molecular Mass : 35.5 kDa
Product-Related Proteins : 32-349
Storage : At -80 centigrade. Avoid repeated freeze-thaw cycles.
Storage Buffer : PBS
Gene Name : WNT7A Wnt family member 7A [ Homo sapiens (human) ]
Official Symbol : WNT7A
Synonyms : WNT7A; Wnt family member 7A; Wnt-7a; protein Wnt-7a; Names; proto-oncogene Wnt7a protein; wingless-type MMTV integration site family, member 7A
Gene ID : 7476
mRNA Refseq : NM_004625
Protein Refseq : NP_004616
MIM : 601570
UniProt ID : O00755

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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