Recombinant Human XRCC4 protein, MYC/DDK-tagged

• Cat.No.: XRCC4-1004H
• Product Overview: Recombinant protein of human X-ray repair complementing defective repair in Chinese hamster cells 4 (XRCC4), transcript variant 1 was expressed in human HEK293 cells.

Specification

• Description: The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 37.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: XRCC4 X-ray repair cross complementing 4 [ Homo sapiens (human) ]
• Official Symbol: XRCC4
• Synonyms: SSMED; SSMED
• Gene ID: 7518
• mRNA Refseq: NM_003401
• Protein Refseq: NP_003392
• MIM: 194363
• UniProt ID: Q13426