Recombinant Human YBX1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: YBX1-4852H
• Product Overview: YBX1 MS Standard C13 and N15-labeled recombinant protein (NP_004550) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 35.9 kDa
• AA Sequence: MSSEAETQQPPAAPPAAPALSAADT KPGTTGSGAGSGGPGGLTSAAPAGG DKKVIATKVLGTVKWFNVRNGYGFI NRNDTKEDVFVHQTAIKKNNPRKYL RSVGDGETVEFDVVEGEKGAEAANV TGPGGVPVQGSKYAADRNHYRRYPR RRGPPRNYQQNYQNSESGEKNEGSE SAPEGQAQQRRPYRRRRFPPYYMRR PYGRRPQYSNPPVQGEVMEGADNQG AGEQGRPVRQNMYRGYRPRFRRGPP RQRQPREDGNEEDKENQGDETQGQQ PPQRRYRRNFNYRRRRPENPKPQDG KETKAADPPAENSSAPEAEQGGAET RTRPLEQKLISEEDLAANDILDYKD DDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: YBX1 Y box binding protein 1 [ Homo sapiens (human) ]
• Official Symbol: YBX1
• Synonyms: YBX1; Y box binding protein 1; NSEP1, nuclease sensitive element binding protein 1; nuclease-sensitive element-binding protein 1; BP 8; CSDA2; CSDB; DBPB; MDR NF1; NSEP 1; YB 1; YB1; CBF-A; EFI-A; DNA-binding protein B; Y-box-binding protein 1; Y-box transcription factor; enhancer factor I subunit A; nuclease sensitive element binding protein 1; CCAAT-binding transcription factor I subunit A; major histocompatibility complex, class II, Y box-binding protein I; BP-8; YB-1; NSEP1; NSEP-1; MDR-NF1; MGC104858; MGC110976; MGC117250
• Gene ID: 4904
• mRNA Refseq: NM_004559
• Protein Refseq: NP_004550
• MIM: 154030
• UniProt ID: P67809