Recombinant Human ZC3H12A protein, Myc/His-tagged

• Cat.No.: ZC3H12A-45H
• Product Overview: Recombinant Human ZC3H12A(1-599 aa) fused with Myc tag at C-terminal and His tag at N-terminal was expressed in HEK293.

Specification

• Description: ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis.
• Source: HEK293
• Species: Human
• Tag: Myc/His
• Form: Tris-based buffer,50% glycerol
• Protein length: 1-599 aa
• AA Sequence: MSGPCGEKPV LEASPTMSLW EFEDSHSRQG TPRPGQELAA EEASALELQM KVDFFRKLGY SSTEIHSVLQ KLGVQADTNT VLGELVKHGT ATERERQTSP DPCPQLPLVP RGGGTPKAPN LEPPLPEEEK EGSDLRPVVI DGSNVAMSHG NKEVFSCRGI LLAVNWFLER GHTDITVFVP SWRKEQPRPD VPITDQHILR ELEKKKILVF TPSRRVGGKR VVCYDDRFIV KLAYESDGIV VSNDTYRDLQ GERQEWKRFI EERLLMYSFV NDKFMPPDDP LGRHGPSLDN FLRKKPLTLE HRKQPCPYGR KCTYGIKCRF FHPERPSCPQ RSVADELRAN ALLSPPRAPS KDKNGRRPSP SSQSSSLLTE SEQCSLDGKK LGAQASPGSR QEGLTQTYAP SGRSLAPSGG SGSSFGPTDW LPQTLDSLPY VSQDCLDSGI GSLESQMSEL WGVRGGGPGE PGPPRAPYTG YSPYGSELPA TAAFSAFGRA MGAGHFSVPA DYPPAPPAFP PREYWSEPYP LPPPTSVLQE PPVQSPGAGR SPWGRAGSLA KEQASVYTKL CGVFPPHLVE AVMGRFPQLL DPQQLAAEIL SYKSQHPSE
• Purity: >90% ( SDS-PAGE )
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
  Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.

Gene Information

• Gene Name: ZC3H12A zinc finger CCCH-type containing 12A [ Homo sapiens ]
• Official Symbol: ZC3H12A
• Synonyms: ZC3H12A; zinc finger CCCH-type containing 12A; ribonuclease ZC3H12A; FLJ23231; MCP induced protein 1; MCPIP1; MCP-induced protein 1; MCP-1 treatment-induced protein; zinc finger CCCH domain-containing protein 12A; MCPIP; dJ423B22.1; RP3-423B22.1
• Gene ID: 80149
• mRNA Refseq: NM_025079
• Protein Refseq: NP_079355
• MIM: 610562
• UniProt ID: Q5D1E8
• Chromosome Location: 1p34.3
• Function: endonuclease activity; hydrolase activity; metal ion binding; protein binding