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Recombinant Human/Cynomolgus CD28(Asn19-Pro152) Protein, N-6*His-tagged

Cat.No. : CD28-339H
Product Overview : Recombinant Human/Cynomolgus CD28(P10747)(Asn19-Pro152) Protein, fused with a 6*His tag at the N-terminus, was produced in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Human/Cynomolgus
Tag : His
Form : Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
Molecular Mass : The recombinant Human/Cynomolgus CD28 Protein has a predicted molecular mass of 16.7kDa, it migrates with an apparent molecular mass of 30-40kDa under reducing conditions.
AA Sequence : Asn19-Pro152
Endotoxin : < 0.01 EU per μg of the protein as determined by the LAL method.
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 mg/ml. Centrifuge the vial at 4°C before opening to recover the entire contents.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name : CD28 CD28 molecule [ Homo sapiens ]
Official Symbol : CD28
Synonyms : CD28; CD28 molecule; CD28 antigen (Tp44); T-cell-specific surface glycoprotein CD28; T cell specific surface glycoprotein; CD28 antigen; Tp44; MGC138290;
Gene ID : 940
mRNA Refseq : NM_001243077
Protein Refseq : NP_001230006
MIM : 186760
UniProt ID : P10747

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can CD28 protein be used for personalized medicine? 01/13/2023

CD28 protein expression and function may be relevant for personalized treatment strategies in autoimmune diseases and cancer.

What are the potential clinical applications of targeting CD28 protein? 05/18/2021

Targeting CD28 protein may have therapeutic potential in treating autoimmune diseases, cancer immunotherapy, and organ transplantation.

How does CD28 protein impact regulatory T cells (Tregs)? 06/21/2019

CD28 signaling is important for the function and maintenance of regulatory T cells, which play a role in immune tolerance and suppression of autoimmunity.

How does CD28 protein impact cancer immunotherapy? 11/26/2018

CD28 protein is involved in enhancing the anti-tumor immune response, making it a potential target for cancer immunotherapy.

Are there any approved therapies targeting CD28 protein? 05/27/2017

Currently, there are no FDA-approved therapies specifically targeting CD28 protein, but research is ongoing in this area.

Customer Reviews (3)

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Reviews
08/24/2021

    Its unique characteristics contribute to obtaining clear and detailed structural information, enabling researchers to unravel the intricate complexities of protein interactions and conformational changes.

    08/24/2021

      Researchers can confidently rely on its capabilities to generate precise and significant results, enhancing the understanding of protein function and dynamics.

      08/06/2021

        the CD28 protein's outstanding performance in ELISA and its utility in protein electron microscopy structure analysis make it a highly recommended tool for researchers.

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