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Recombinant Influenza [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA) protein, His-tagged

Cat.No. : NA-346I
Product Overview : Recombinant Influenza [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA) protein (His36-Lys449), fused to His tag at N-terminus, was expressed in human 293 cells (HEK293).
  • Specification
  • Gene Information
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Description : Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
Source : HEK293
Species : Influenza [A/Thailand/1(KAN-1)/2004(H5N1)]
Tag : His
Form : Lyophilized from 0.22 um filtered solution in PBS, pH7.4, 10% trehalose.
Molecular Mass : The protein has a calculated MW of 46.1 kDa. The protein migrates as 48 kDa under reducing (R) condition (SDS-PAGE).
Protein length : 414
Endotoxin : Less than 1.0 EU per ug by the LAL method.
Purity : >92% as determined by SDS-PAGE.
Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Official Symbol : NA
UniProt ID : H8PF47
Official Symbol : NA
UniProt ID : H8PF47

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there NA protein-based therapies in clinical use? 05/01/2023

Yes, some RNA-based therapies target specific NA proteins for conditions like spinal muscular atrophy.

How do histones relate to epigenetic modifications and clinical outcomes? 08/07/2019

Changes in histone modifications can influence gene expression and contribute to various diseases.

How are NA proteins used in cancer research and treatment? 03/20/2019

NA proteins are studied to understand oncogenesis, and some drugs target NA protein interactions to treat cancer.

Can NA proteins be used for gene therapy? 07/18/2018

NA proteins can be involved in gene therapy strategies to manipulate gene expression for therapeutic purposes.

How are NA proteins involved in the regulation of cell cycle and cancer progression? 12/05/2016

NA proteins control the cell cycle, and dysregulation can contribute to uncontrolled cell growth seen in cancer.

Customer Reviews (3)

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Reviews
11/26/2020

    I highly recommend the NA protein for a variety of experimental applications.

    09/08/2019

      I enthusiastically recommend the NA protein to fellow researchers who seek an unparalleled product accompanied by dedicated customer assistance.

      11/16/2018

        the NA protein stands out for its exceptional quality, coupled with the outstanding technical support delivered by the manufacturer.

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