Recombinant Mouse Ankrd16 Protein, Myc/DDK-tagged

• Cat.No.: Ankrd16-1631M
• Product Overview: Purified recombinant protein of mouse full-length ankyrin repeat domain 16 (Ankrd16), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Required to prevent the misactivation of serine (Ser) with tRNA(Ala) by promoting the hydrolysis of Ser-mischarged tRNA(Ala), thereby playing a role in translational fidelity. Binds directly to the catalytic domain of AARS/AlaRS and captures Ser that is misactivated by AARS/AlaRS, preventing the charging of Ser adenylates to tRNA(Ala) and precluding Ser misincorporation in nascent peptides.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 39.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ankrd16 ankyrin repeat domain 16 [ Mus musculus (house mouse) ]
• Official Symbol: Ankrd16
• Synonyms: Ankrd16; ankyrin repeat domain 16; AI646698; 2810455F06Rik; D430029B21Rik; ankyrin repeat domain-containing protein 16
• Gene ID: 320816
• mRNA Refseq: NM_177268
• Protein Refseq: NP_796242
• UniProt ID: A2AS55