Recombinant Mouse Arhgap29 Protein, Myc/DDK-tagged

• Cat.No.: Arhgap29-1686M
• Product Overview: Purified recombinant protein of mouse full-length Rho GTPase activating protein 29 (Arhgap29), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 142.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arhgap29 Rho GTPase activating protein 29 [ Mus musculus (house mouse) ]
• Official Symbol: Arhgap29
• Synonyms: ARHGAP29; Rho GTPase activating protein 29; rho GTPase-activating protein 29; PTPL1-associated RhoGAP 1; rho-type GTPase-activating protein 29; Parg1; C76601; AU040217; A830014I19; 6720461J18Rik; B130017I01Rik
• Gene ID: 214137
• mRNA Refseq: NM_172525
• Protein Refseq: NP_766113
• UniProt ID: Q8CGF1