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Recombinant Mouse Atp5a1 protein, Myc/DDK-tagged

Cat.No. : ATP5A1-2129M
Product Overview : Recombinant Mouse Sema3c protein, fused to Myc/DDK-tag at C-terminus, was expressed in human 293 cells (HEK293).
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Description : This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c).
Source : HEK293
Species : Mouse
Tag : Myc/DDK
Form : 3438 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 59.8 kDa
Purity : >80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 μg/mL as determined by microplate BCA method
Gene Name : Atp5a1
Official Symbol : Atp5a1
Synonyms : Atpm; Mom2; Atp5f1a; AI035633; AL022851; AL023067; D18Ertd206e
Gene ID : 11946
mRNA Refseq : NM_007505.2
Protein Refseq : NP_031531.1
UniProt ID : D3Z6F5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What other proteins does ATP5Ainteract with? 02/22/2022

ATP5A1 interacts with other ATP synthase subunits and a variety of mitochondrial proteins (such as NADH dehydrogenase and chromosomal acyl-coa carboxylase) to participate in the process of energy metabolism.

Is the abnormal expression of ATP5Avaluable in the diagnosis and prognosis of neurodegenerative diseases? 07/14/2021

The abnormal expression of ATP5A1 can be used as an important indicator for the diagnosis and prognosis of some neurodegenerative diseases, but it needs to be comprehensively analyzed in combination with other clinical and molecular biological results.

What is the mutation mechanism of ATP5A1? 12/26/2020

Mutations in ATP5A1 may lead to abnormal changes in its intracellular localization and function, thereby affecting mitochondrial neuroregulation and energy metabolism.

What is the role of ATP5Ain biological development? 11/13/2020

ATP5A1 participates in the regulation of cellular energy metabolism and mitochondrial function, and plays an important role in cell growth and development.

Are there any studies on drugs for ATP5Aregulating cellular energy metabolism? 09/30/2020

Yes, several studies have been devoted to the development of drugs that can regulate the activity of ATP5A1 to affect cellular energy metabolism and treat related diseases.

Is the expression pattern of ATP5Aassociated with liver cancer or other tumors? 01/01/2019

Yes, some studies have found that the expression pattern of ATP5A1 is related to the malignant degree and prognosis of liver cancer, bladder cancer, prostate cancer and other tumors.

Customer Reviews (3)

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08/04/2020

    It is not easy to be contaminated, and then stored.

    11/29/2019

      The reproducibility of ATP5A1 is very good, with very consistent results in every experiment or application, benefiting from its high degree of stability and reproducibility.

      05/30/2019

        Using ATP5A1 as a catalyst, the rate and yield of chemical reactions can be significantly increased with high catalytic efficiency.

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