Recombinant Mouse Atxn10 Protein, Myc/DDK-tagged
Cat.No. : | Atxn10-1783M |
Product Overview : | Purified recombinant protein of mouse full-length ataxin 10 (Atxn10), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 53.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Atxn10 ataxin 10 [ Mus musculus (house mouse) ] |
Official Symbol : | Atxn10 |
Synonyms : | ATXN10; ataxin 10; ataxin-10; brain protein E46; spinocerebellar ataxia 10; testis expressed gene 169; spinocerebellar ataxia type 10 protein homolog; E46; Sca10; C77170; Tex169; TEG-169; AI325283 |
Gene ID : | 54138 |
mRNA Refseq : | NM_016843 |
Protein Refseq : | NP_058539 |
UniProt ID : | P28658 |
Products Types
◆ Recombinant Protein | ||
ATXN10-306R | Recombinant Rhesus Macaque ATXN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATXN10-900M | Recombinant Mouse ATXN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATXN10-557R | Recombinant Rat ATXN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATXN10-3037H | Recombinant Human ATXN10 Protein, MYC/DDK-tagged | +Inquiry |
ATXN10-79C | Recombinant Cynomolgus Monkey ATXN10 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ATXN10-51HCL | Recombinant Human ATXN10 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe research of ATXN10 protein mainly focuses on understanding its functional regulation mechanism, its relationship with the pathogenesis of SCA10, and the search for therapeutic methods for SCA10. At present, several important advances have been made regarding the function of ATXN10 protein and the pathogenesis of SCA10.
ATXN10 protein is involved in the regulation of a variety of neural cell functions, including transcription regulation, RNA processing, cell cycle regulation, etc. It plays an important role in the development and functional maintenance of the nervous system.
The function of ATXN10 protein is regulated by a variety of regulatory mechanisms, including the binding of transcriptional regulators and post-translational modifications. These regulatory mechanisms ensure the adaptability and stability of ATXN10 protein.
Yes, the ATXN10 protein interacts with multiple proteins to form complexes involved in the regulation of a variety of cellular functions. For example, ATXN10 interacts with TATA box binding protein (TBP) and participates in transcriptional regulation.
In addition to SCA10, ATXN10 protein has been implicated in the development and progression of other neurological diseases. For example, it may be associated with the pathogenesis of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. However, further studies are needed to confirm these associations.
The protein is associated with spinocerebellar ataxia type 10 (SCA10). SCA10 is an inherited neurodegenerative disorder characterized by dysfunction of the cerebellum and spinal cord leading to ataxia and other neurological symptoms.
Customer Reviews (3)
Write a reviewIt's the most biologically active protein I've ever seen, and the purity of its production is impressive.
This production process of Atxn10 uses renewable resources as raw materials, making the production process more environmentally friendly and sustainable.
The short half-life and high clearance of Atxn10 make them more safe and effective in clinical application.
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