Recombinant Mouse B3galnt2 Protein, Myc/DDK-tagged

• Cat.No.: B3galnt2-1799M
• Product Overview: Purified recombinant protein of mouse full-length UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2 (B3galnt2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 57.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: B3galnt2 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2 [ Mus musculus (house mouse) ]
• Official Symbol: B3galnt2
• Synonyms: B3GALNT2; UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 2; UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2; beta-1,3-GalNAc-T2; beta-1,3-N-acetylgalactosaminyltransferase II; C80633; A930105D20Rik; D230016N13Rik; MGC103263
• Gene ID: 97884
• mRNA Refseq: NM_178640
• Protein Refseq: NP_848755
• UniProt ID: Q8BG28