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Recombinant Mouse Bpi Protein, Myc/DDK-tagged

Cat.No. : Bpi-1885M
Product Overview : Purified recombinant protein of mouse full-length bactericidal permeablility increasing protein (Bpi), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 54.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Bpi bactericidal permeablility increasing protein [ Mus musculus (house mouse) ]
Official Symbol : Bpi
Synonyms : BPI; bactericidal permeablility increasing protein; bactericidal permeability-increasing protein; bactericidal/permeability-increasing protein; Bpifd1; 9230105K17Rik
Gene ID : 329547
mRNA Refseq : NM_177850
Protein Refseq : NP_808518
UniProt ID : Q67E05

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What experimental techniques are commonly used to study BPI, including its structure, interactions, and functional activities in immune responses? 03/24/2022

Techniques such as X-ray crystallography, surface plasmon resonance, and functional assays are commonly used to study BPI. These approaches provide insights into its structure, interactions, and immune modulatory activities.

How does BPI participate in the regulation of the inflammatory response, and what molecular mechanisms underlie its interaction with immune cells? 08/05/2021

BPI regulates the inflammatory response by interacting with immune cells and modulating signaling pathways. Its binding to lipopolysaccharides and subsequent interactions influence immune cell activation and cytokine production.

In the context of sepsis and other infectious diseases, how does BPI contribute to the host's response, and are there therapeutic implications for modulating BPI activity? 02/09/2020

BPI plays a crucial role in the host response to sepsis and infectious diseases. Understanding its contribution may unveil therapeutic strategies for modulating BPI activity to enhance host defense mechanisms.

How does BPI influence neutrophil functions, and what role does it play in the coordination of immune responses against extracellular bacteria? 07/06/2019

BPI influences neutrophil functions by modulating their activation and bactericidal activities. Its role in coordinating immune responses against extracellular bacteria is crucial for efficient host defense.

How does BPI participate in the regulation of the complement system, and what implications does this have for immune response coordination? 10/27/2018

BPI interacts with the complement system, influencing immune response coordination. Its regulatory role in complement activation contributes to the orchestration of the immune response against pathogens.

Customer Reviews (3)

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Reviews
01/25/2021

    A product of exceptional quality, paired with customer service that is both attentive and efficient.

    05/14/2020

      Timely delivery made the experience even better.

      10/02/2018

        Great product quality, friendly customer service, and quick delivery

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