Active Recombinant Mouse CD276, MIgG2a Fc-tagged
Cat.No. : | CD276-2881M |
Product Overview : | The extracellular domain of mouse B7-H3 (NP_598744.1) (Glu30-Ala248) is fused to the N-terminus of the Fc region of mouse IgG2a. |
- Specification
- Gene Information
- Related Products
Source : | CHO cells |
Species : | Mouse |
Tag : | MIgG2a Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to enhance anti-CD3-induced proliferation of mouse CD3+ T cells. |
Molecular Mass : | 50KDa (monomer) |
AA Sequence : | Glu30-Ala248 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | Cd276 CD276 antigen [ Mus musculus ] |
Official Symbol : | CD276 |
Synonyms : | CD276; CD276 antigen; B7-H3; B7 homolog 3; costimulatory molecule; B7h3; B7RP-2; AU016588; 6030411F23Rik; |
Gene ID : | 102657 |
mRNA Refseq : | NM_133983 |
Protein Refseq : | NP_598744 |
Pathway : | Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; |
Function : | receptor binding; receptor binding; |
Products Types
◆ Recombinant Protein | ||
Cd276-219M | Recombinant Mouse Cd276 Protein, MYC/DDK-tagged | +Inquiry |
Cd276-1140M | Recombinant Mouse Cd276 protein(Met1-Phe244), His-tagged, Biotinylated | +Inquiry |
CD276-0766H | Recombinant Human CD276 Protein, His-Flag-StrepII-Tagged | +Inquiry |
CD276-1238H | Recombinant Human CD276 protein(Met1-Thr243), His-tagged | +Inquiry |
CD276-502H | Recombinant Human CD276 Protein (ECD) (Met1-Thr461), HIgG1 Fc-tagged, Biotinylated | +Inquiry |
◆ Lysates | ||
CD276-001MCL | Recombinant Mouse CD276 cell lysate | +Inquiry |
CD276-1959HCL | Recombinant Human CD276 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (5)
Ask a questionCD276 has been associated with autoimmune diseases and certain inflammatory conditions. Exploring its role in these diseases may open avenues for therapeutic interventions.
Research suggests that CD276 expression levels may serve as a diagnostic biomarker for certain cancers. Detection methods, such as immunohistochemistry, are being explored to assess CD276 levels in tumor tissues.
CD276 can modulate the tumor microenvironment by suppressing immune responses, promoting angiogenesis, and supporting tumor cell survival. Understanding these interactions is crucial for developing targeted therapies.
Yes, several clinical trials are underway to evaluate the safety and efficacy of CD276-targeted therapies in different cancer types. These trials aim to assess the impact on patient outcomes and potential side effects.
CD276-targeted therapy focuses on modulating the immune response against cancer cells, whereas traditional treatments like chemotherapy and radiation target rapidly dividing cells, including both healthy and cancerous cells.
Customer Reviews (3)
Write a reviewIt has consistently demonstrated high sensitivity and accuracy in detecting and quantifying target molecules, allowing for precise and reliable measurement of analytes in my experimental samples.
Its versatility and reliability make it an excellent choice for research applications, and I highly recommend it to fellow scientists.
The sensitivity and specificity of the CD276 Protein have consistently delivered robust and consistent results, enhancing the efficiency and accuracy of my experimental workflows.
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