Active Recombinant Mouse Cd40lg Protein
Cat.No. : | Cd40lg-2063M |
Product Overview : | Purified recombinant protein of Mouse CD40 ligand (Cd40lg) without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B. Induces the activation of kinases MAPK8 and PAK2 in T-cells. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. |
Source : | E. coli |
Species : | Mouse |
Bio-activity : | Determined by its ability to induce TNF-alpha; and MIP-1alpha; production by murine splenocytes. The expected ED50 for this effect is > 0.1 μg/mL. |
Molecular Mass : | 16.4 kDa |
AA Sequence : | MQRGDEDPQIAAHVVSEANSNAASV LQWAKKGYYTMKSNLVMLENGKQLT VKREGLYYVYTQVTFCSNREPSSQR PFIVGLWLKPSSGSERILLKAANTH SSSQLCEQQSVHLGGVFELQAGASV FVNVTEASQVIHRVGFSSFGLLKL |
Endotoxin : | < 0.1 ng/μg of protein (< 1 EU/μg) |
Purity : | > 95% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. |
Storage Buffer : | LyopH ilized from a 0.2 μM filtered solution of 20 mM pH ospH ate buffer, 100 mM NaCl, pH 7.2 |
Gene Name : | Cd40lg CD40 ligand [ Mus musculus (house mouse) ] |
Official Symbol : | Cd40lg |
Synonyms : | Cd40lg; CD40 ligand; IGM; IMD; gp3; Cd40; HIGM; IMD3; Ly-6; Ly62; T-BA; TRAP; Tnfs; gp39; CD154; Cd40l; HIGM1; Ly-62; T-BAM; CD40-L; Tnfsf5; Tnlg8b; CD40 ligand; T-cell antigen Gp39; TNF-related activation protein; tumor necrosis factor ligand 8b; tumor necrosis factor ligand superfamily member 5 |
Gene ID : | 21947 |
mRNA Refseq : | NM_011616 |
Protein Refseq : | NP_035746 |
UniProt ID : | P27548 |
Products Types
◆ Recombinant Protein | ||
CD40LG-323H | Active Recombinant Human CD40LG Protein (Met1-Leu261), C-His tagged, Animal-free, Carrier-free | +Inquiry |
CD40LG-635H | Recombinant Human CD40LG Protein, Fc-tagged | +Inquiry |
CD40LG-12H | Active Recombinant Human CD40LG Protein (116-261), N-FLAG tagged, Certified Serum Grade | +Inquiry |
CD40LG-38H | Active Recombinant Human CD40LG Protein | +Inquiry |
CD40LG-911R | Recombinant Rat CD40LG Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CD40LG-1965HCL | Recombinant Human CD40LG cell lysate | +Inquiry |
CD40LG-1205RCL | Recombinant Rat CD40LG cell lysate | +Inquiry |
CD40LG-1548MCL | Recombinant Mouse CD40LG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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