Recombinant Mouse Cgas Protein, Myc/DDK-tagged
Cat.No. : | Cgas-2132M |
Product Overview : | Purified recombinant protein of mouse full-length cyclic GMP-AMP synthase (Cgas), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 58.2 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Cgas cyclic GMP-AMP synthase [ Mus musculus (house mouse) ] |
Official Symbol : | Cgas |
Synonyms : | Cgas; cyclic GMP-AMP synthase; Mb21d1; E330016A19Rik; cyclic GMP-AMP synthase; 2'3'-cGAMP synthase; Mab-21 domain containing 1; cGAMP synthase; mab-21 domain-containing protein 1; EC 2.7.7.86 |
Gene ID : | 214763 |
mRNA Refseq : | NM_173386 |
Protein Refseq : | NP_775562 |
UniProt ID : | Q8C6L5 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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