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Recombinant Mouse Cntfr Protein, MYC/DDK-tagged

Cat.No. : CNTFR-3683M
Product Overview : Purified recombinant protein of Mouse ciliary neurotrophic factor receptor (Cntfr), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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  • Gene Information
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Description : This gene encodes the alpha subunit of the ciliary neurotrophic factor (CNTF) receptor that triggers the assembly of a trimolecular complex upon binding to CNTF, and initiate a downstream signaling process. The encoded preproprotein undergoes proteolytic processing to generate a glycosylphosphatidylinositol-linked cell surface protein. Mice lacking the encoded protein die shortly after birth and exhibit a reduction of motoneuron number at birth. The transgenic disruption of this gene specifically in the skeletal muscle followed by a peripheral nerve lesion impairs motor neuron axonal regeneration across the lesion site. Alternative splicing of this gene results in multiple transcript variants.
Source : HEK293T
Species : Mouse
Tag : MYC/DDK
Molecular Mass : 40.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cntfr ciliary neurotrophic factor receptor [ Mus musculus (house mouse) ]
Official Symbol : Cntfr
Synonyms : Cntfr; ciliary neurotrophic factor receptor; Cntfralpha; ciliary neurotrophic factor receptor subunit alpha; CNTF receptor subunit alpha
Gene ID : 12804
mRNA Refseq : NM_016673
Protein Refseq : NP_057882
UniProt ID : O88507

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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