Recombinant Mouse Dhodh Protein, Myc/DDK-tagged
Cat.No. : | Dhodh-2546M |
Product Overview : | Purified recombinant protein of mouse full-length dihydroorotate dehydrogenase (Dhodh), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
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Description : | Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 42.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Dhodh dihydroorotate dehydrogenase [ Mus musculus (house mouse) ] |
Official Symbol : | Dhodh |
Synonyms : | DHODH; dihydroorotate dehydrogenase; dihydroorotate dehydrogenase (quinone), mitochondrial; DHOdehase; dihydroorotate oxidase; dihydroorotate dehydrogenase, mitochondrial; AI834883; 2810417D19Rik |
Gene ID : | 56749 |
mRNA Refseq : | NM_020046 |
Protein Refseq : | NP_064430 |
UniProt ID : | O35435 |
Products Types
◆ Recombinant Protein | ||
DHODH-2590H | Recombinant Human DHODH Protein, GST-tagged | +Inquiry |
DHODH-01H | Active Recombinant Human DHODH Protein, Met/His-tagged | +Inquiry |
DHODH-2541M | Recombinant Mouse DHODH Protein (31-395 aa), His-tagged | +Inquiry |
DHODH-1517R | Recombinant Rat DHODH Protein, His (Fc)-Avi-tagged | +Inquiry |
DHODH-2355M | Recombinant Mouse DHODH Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
DHODH-6944HCL | Recombinant Human DHODH 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIt catalyzes a key step in the pyrimidine biosynthesis pathway, converting dihydroorotate to orotate.
DHODH, dihydroorotate dehydrogenase, is crucial for the de novo synthesis of pyrimidines, essential for DNA and RNA synthesis.
DHODH collaborates with other enzymes in pyrimidine biosynthesis, playing a role in nucleotide metabolism.
DHODH is important for cell proliferation, as pyrimidine synthesis is essential for DNA replication and cell growth.
Genetic mutations in DHODH can disrupt nucleotide synthesis, affecting cellular replication and function.
Altered DHODH activity is linked with autoimmune conditions, as it affects lymphocyte proliferation and function.
Targeting DHODH in therapies could be effective in treating autoimmune diseases and certain cancers by modulating pyrimidine synthesis.
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