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Recombinant Mouse Dhodh Protein, Myc/DDK-tagged

Cat.No. : Dhodh-2546M
Product Overview : Purified recombinant protein of mouse full-length dihydroorotate dehydrogenase (Dhodh), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
  • Specification
  • Gene Information
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Description : Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 42.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Dhodh dihydroorotate dehydrogenase [ Mus musculus (house mouse) ]
Official Symbol : Dhodh
Synonyms : DHODH; dihydroorotate dehydrogenase; dihydroorotate dehydrogenase (quinone), mitochondrial; DHOdehase; dihydroorotate oxidase; dihydroorotate dehydrogenase, mitochondrial; AI834883; 2810417D19Rik
Gene ID : 56749
mRNA Refseq : NM_020046
Protein Refseq : NP_064430
UniProt ID : O35435

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does DHODH contribute to pyrimidine biosynthesis? 08/28/2022

It catalyzes a key step in the pyrimidine biosynthesis pathway, converting dihydroorotate to orotate.

What is the primary role of DHODH in cellular metabolism? 10/23/2020

DHODH, dihydroorotate dehydrogenase, is crucial for the de novo synthesis of pyrimidines, essential for DNA and RNA synthesis.

How does DHODH interact with other enzymes in the pyrimidine biosynthesis pathway? 10/27/2018

DHODH collaborates with other enzymes in pyrimidine biosynthesis, playing a role in nucleotide metabolism.

What role does DHODH play in cell proliferation and growth? 05/07/2018

DHODH is important for cell proliferation, as pyrimidine synthesis is essential for DNA replication and cell growth.

How do genetic variations in DHODH affect its function in nucleotide synthesis? 12/29/2017

Genetic mutations in DHODH can disrupt nucleotide synthesis, affecting cellular replication and function.

What is the impact of altered DHODH activity on autoimmune diseases? 08/01/2017

Altered DHODH activity is linked with autoimmune conditions, as it affects lymphocyte proliferation and function.

What potential therapeutic applications arise from targeting DHODH in disease treatment? 07/17/2017

Targeting DHODH in therapies could be effective in treating autoimmune diseases and certain cancers by modulating pyrimidine synthesis.

Customer Reviews (3)

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Reviews
07/29/2020

    Saves time and effort. Highly recommended for research.

    11/03/2017

      Top-notch support for insights. Trusted for accurate data.

      05/05/2017

        Reliable data, essential for our protein research.

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